Not known Facts About Allergy and Clinical Immunology
An additional DNA-based strategy has long been to mix allergen with bacterial DNA sequences that consist of CpG motifs to selectively goal Toll-like receptor 9 (TLR9) expressed on human B cells and dendritic cells. The major ragweed pollen allergen Amb a one covalently associated with a B-form CpG-that contains oligodeoxynucleotide (ODN)131 was pro